Endocrine Abstracts

Both low-frequency electro-acupuncture (EA) and manual acupuncture improve menstrual frequency and decrease circulating androgens in women with polycystic ovary syndrome (PCOS). We sought to determine whether low-frequency EA is more effective than manual stimulation in regulating disturbed estrous cyclicity in rats with PCOS induced by 5α-dihydrotestosterone (DHT). To identify the central mechanisms of the effects of stimulation, we assessed hypothalamic mRNA expression ...

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders affecting reproductive women. Treatments with Chinese herbal mixtures (HM) and electro-acupuncture (EA) have been proven efficient in clinic. This study evaluated the peripheral and central effects of HM and EA in dihydrotestosterone (DHT)-induced PCOS rats. The female Wistar rats were divided into control (C), control with placebo (CP), DHT-induced PCOS model (PCOS), PCOS model exposed to herbal mi...